Paula D. Zook, MD, FAAD

With over 21 years of clinical experience, Dr. Paula Zook is a highly respected leader in the Seattle medical community. A graduate of the University of Washington School of Medicine, Dr. Zook has dedicated her career to the intersection of complex medical dermatology and the art of regenerative medicine.

As a Board-Certified Dermatologist and a Fellow of the American Academy of Dermatology (FAAD), she offers a rare depth of expertise that spans from life-saving skin cancer diagnosis to advanced aesthetic rejuvenation. Dr. Zook is recognized nationally for her contributions to clinical research—having served as a lead investigator on dozens of clinical trials for psoriasis, atopic dermatitis, and acne—and for her specialized work in complex conditions like vulvar dermatology.

Whether she is performing a meticulous full-body skin exam or utilizing the latest energy-based lasers for skin rejuvenation, Dr. Zook’s approach remains the same: a commitment to excellence rooted in the unique needs of every individual she treats.

Areas of Expertise:

• Skin Cancer: Advanced diagnosis, prevention, and surgical treatment.
• Complex Medical Dermatology: Expert management of chronic and inflammatory skin conditions.
• Hair Loss: Comprehensive diagnostic and therapeutic solutions.
• Regenerative Aesthetics: Utilizing laser and energy-based technologies to restore skin health and vitality.

Advancing the Future of Dermatology

With over two decades of experience in clinical research, Dr. Paula Zook has served as a Lead Investigator on more than 30 Phase II and Phase III clinical trials. Her work has been instrumental in the development of many of the breakthrough biologics and topical therapies used in modern dermatology today.

Key Research Focus Areas:

• Psoriasis & Psoriatic Arthritis: Leading extensive 52-week safety and efficacy studies for next-generation biologics (including Ixekizumab and Guselkumab).

• Atopic Dermatitis (Eczema): Investigating novel systemic and topical treatments, such as Dupilumab, to improve long-term disease maintenance and patient quality of life.

• Complex Inflammatory Conditions: Specialized research into the treatment of Hidradenitis Suppurativa, Acne Vulgaris, and Primary Axillary Hyperhidrosis (excessive sweating).

• Vulvar Health & Gynecology: Author of "Diseases of The Vulva" for the American College of Physicians, providing a bridge between dermatology and specialized women's health.

"My background in clinical trials allows me to offer my patients a deeper understanding of the science behind their treatments. It gives us a window into the newest, most effective ways to manage even the most complex skin conditions."
— Dr. Paula Zook